Researchers believe that evolution is the root cause of Diabetes. Evolution is the transformation over time in the proportion of an individual being that is contrary in one or more inherited traits. Evolution occurs when there is a variation of inborn traits. Classifications of variation are mutation, genetic recombination, and gene flow.
Study has been conducted on Stanford University School of Medicine and they have recognized genetic variations in a hormone are concerned in the discharge of insulin - the substance that is responsible in regulating insulin. High blood sugar is linked with the development of diabetes that normally once the body is incapable of creating its own insulin.
The findings could help doctors to better know diabetes and find a way to cure it permanently. It shows that the disease progresses as our predecessor change from being hunters to be dependent in agriculture in the way of living.
According to Sheau Yu "Teddy" Hsu, PhD, assistant professor of obstetrics and gynecology and senior author of the study, there are 207 genetic areas, which can be connected to diabetes and obesity. They are able to identify the prevalence in the time since humans began depart from Africa about 60,000 years ago. 59 regions are identified in about 30% of the people in the HapMap project - a universal review distinction among inhabitants.
The researchers are able to distinguish around five genes with hereditary differences that appear regularly on Asians and/or Europeans, but not on Africans. One of the five genes is GIP (Glucanase Inhibitor Protein) and they found it as the most interesting among them. GIP stimulates insulin secretion in humans following a meal.
They agreed on one fact that the there are three individual transformations in the regions of GIP, the DNA closest to the GIP gene which also affects when and how it is transformed into protein - decreases the concentration of the hormone.
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